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For
the treatment of Parkinson's disease
PK-Merz is an effective therapeutic
principle which rapidly and comprehensively
improves the principal and troublesome
symptoms rigor, tremor and akinesia.
Thus the patient becomes more independent
in performing the activities of everyday
life: getting up become easier, walking
steadier and the movements are less
restricted. Particularly impressive
are the psychic brightening and the
increased interest in the surroundings.
The
sulphate compound of amantadine developed
by Merz Adamantane Research for the
treatment of Parkinsonism has the
great therapeutic advantage that this
comprehensive effect is achieved with
good tolerance. Therefore, PK-Merz
is also especially suitable for out-patient
treatment.
PRESENTATION:
Orange coloured film coated tablets.
COMPOSITION:
Each film coated tablet contains:
Amantadine Sulphate 100mg
INDICATIONS:
Pk-Merz
(Amantadine Sulphate) has been indicated
for the treatment of Hepatitis-C.
It has been promoted in this particular
segment for quite some time but recently
this wonder drug has been acknowledged
by the physicians and gasteroenterologists
as a break through in treating Hepatitis-C;
especially when used in combination
regimen with interferon and ribavirin.
Parkinsonism
of varying origin, senile Parkinsonism,
residual symptoms and residual discomfort
after stereo tactic operations:
- Post-zoster
neuralgia
- Drug
induced extra pyramidal syndrome
DOSAGE:
1) For Hepatitis-C
1 tablet twice daily for six months
2) For Parkinsonism
1 tablet twice daily
After 4 weeks 1 tablet three times
a day
3)
For Post-zoster neuralgia and drug-induced
Parkinsonism
1 tablet twice daily
4)
In advanced cases of Parkinsonism
500mg/day can be given.
The
last daily dose should preferably
be taken by late afternoon to avoid
sleep disturbance.
PK-Merz
tablets may be combined with other
anti-Parkinsonism preparations.
CONTRA-INDICATIONS:
Absolute:
Closed-angle glaucoma, myasthenia
gravis and pregnancy. Patients in
excited or confused states.
Relative:
Open-angle glaucoma, severe hepatic
insufficiency, severe renal insufficiency,
prostate adenoma, tendency towards
hypotension, epilepsy
SIDE-EFFECTS:
Occasional dryness of the mouth, visual
disturbances, constipation, dysuriaand
central nervous disturbances in older
arteriosclerotic patients.
INTERACTIONS:
Anticholinergics can potentiate the
action.
Pack:
Blister pack of 2x10's
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